Projects The projects run by members of the Infectious Disease Dynamics Group at JHU run the gamut of the study of disease dynamics - from primary data collection, to methodological research, to policy engagements. Current Projects Cholera in Bangladesh Clinical, serological and microbial surveillance to understand cholera in Bangladesh. Global Cholera Epidemiology and Control Refining our understanding of the burden of cholera and ways in which we can better use cholera vaccine Hepatitis E in Bangladesh We aim to better understand the epidemiology of Hepatitis E with clinical, serologic, genomic, and human behavior data. Vaccine Impact Modelling Consortium (VIMC) We work with several research groups modeling the impact of vaccination programmes worldwide. Seroanalytics Hub For this project, we take computational approaches to understanding integrated, multipathogen serological surveillance. Human Mobility Modeling Through this project, we aim to model human mobility patterns and understand how travel impacts the spatial and temporal dynamics of various infectious diseases. Multi-Pathogen Scenario Modeling and Forecasting Integrating multiple models for short-term forecasts and longer-term scenario projections of multiple pathogens. Malaria Genomics This work aims to understand the utility of malaria parasite genomics to understand patterns of connectivity and transmission particularly in Sub-Saharan Africa. HCV/HIV Modeling in People Who Inject Drugs (PWID) Through this project, we aim to characterize PWID networks in the Baltimore Metropolitan Area to identify risk factors for HIV and HCV transmission in this population and understand how interventions and behavioral changes might impact transmission. Impact of Cholera Vaccine in Uvira, DRC An in-depth study of the impact of mass cholera vaccination in Uvira, South Kivu, DR Congo. The Child Health and Mortality Prevention Surveillance Project (CHAMPS) The CHAMPS project aims to identify the definitive causes of child deaths and stillbirths in high burden countries to inform policies and programs to prevent child deaths. Serological Modeling for Vaccine-Preventable Diseases (VPDs) Generating, analyzing, and modeling serological data on vaccine-preventable diseases (VPDs) and other infectious diseases to better understand vaccination coverage, transmission rates, and immunity gaps. Identifying Henipavirus Spillovers in Bangladesh Investigating the dynamics of viral spillover at the human-animal interface using serological, molecular, and human and animal behavioral survey data. HIV and STI Surveillance in Eastern and Southern Africa We work closely with the Rakai Health Sciences Program and other collaborators to study HIV transmission in sub-Saharan Africa. Modeling Dynamic Disease-Behavior Feedbacks Integrating models of human behavior and decision making during epidemics into infectious disease transmission models. Center for Accelerating Modeling Utilization and Synthesis (CAMUS) Establishing centers of expertise in applied infectious disease modeling and advancing training programs for modelers, before the next pandemic. Within-Host HIV Modeling Developing mathematical models of HIV drug action within individual patients to predict the outcomes of novel therapeutics. Legacy Projects COVID-19 (Legacy Project) An in-depth summary of our initial COVID projects. Cross-Sectional Incidence Testing Developing and validating testing algorithms to generate point estimates of HIV and HCV incidence. Immune Landscapes of Human Influenza in Households, Towns, and Cities in Southern China Characterizing the immune landscapes of human influenza in southern China. Phylogenetic Study Design Developing methods to estimate informative sample sizes for phylogenetic studies. People IDD is made up of faculty, post-docs, graduate and undergraduate students who are interested in the dynamics of a wide span of infectious diseases. Research Topics Our multi-dimensional projects cover a number of diseases and research topics.
Cholera in Bangladesh Clinical, serological and microbial surveillance to understand cholera in Bangladesh.
Global Cholera Epidemiology and Control Refining our understanding of the burden of cholera and ways in which we can better use cholera vaccine
Hepatitis E in Bangladesh We aim to better understand the epidemiology of Hepatitis E with clinical, serologic, genomic, and human behavior data.
Vaccine Impact Modelling Consortium (VIMC) We work with several research groups modeling the impact of vaccination programmes worldwide.
Seroanalytics Hub For this project, we take computational approaches to understanding integrated, multipathogen serological surveillance.
Human Mobility Modeling Through this project, we aim to model human mobility patterns and understand how travel impacts the spatial and temporal dynamics of various infectious diseases.
Multi-Pathogen Scenario Modeling and Forecasting Integrating multiple models for short-term forecasts and longer-term scenario projections of multiple pathogens.
Malaria Genomics This work aims to understand the utility of malaria parasite genomics to understand patterns of connectivity and transmission particularly in Sub-Saharan Africa.
HCV/HIV Modeling in People Who Inject Drugs (PWID) Through this project, we aim to characterize PWID networks in the Baltimore Metropolitan Area to identify risk factors for HIV and HCV transmission in this population and understand how interventions and behavioral changes might impact transmission.
Impact of Cholera Vaccine in Uvira, DRC An in-depth study of the impact of mass cholera vaccination in Uvira, South Kivu, DR Congo.
The Child Health and Mortality Prevention Surveillance Project (CHAMPS) The CHAMPS project aims to identify the definitive causes of child deaths and stillbirths in high burden countries to inform policies and programs to prevent child deaths.
Serological Modeling for Vaccine-Preventable Diseases (VPDs) Generating, analyzing, and modeling serological data on vaccine-preventable diseases (VPDs) and other infectious diseases to better understand vaccination coverage, transmission rates, and immunity gaps.
Identifying Henipavirus Spillovers in Bangladesh Investigating the dynamics of viral spillover at the human-animal interface using serological, molecular, and human and animal behavioral survey data.
HIV and STI Surveillance in Eastern and Southern Africa We work closely with the Rakai Health Sciences Program and other collaborators to study HIV transmission in sub-Saharan Africa.
Modeling Dynamic Disease-Behavior Feedbacks Integrating models of human behavior and decision making during epidemics into infectious disease transmission models.
Center for Accelerating Modeling Utilization and Synthesis (CAMUS) Establishing centers of expertise in applied infectious disease modeling and advancing training programs for modelers, before the next pandemic.
Within-Host HIV Modeling Developing mathematical models of HIV drug action within individual patients to predict the outcomes of novel therapeutics.
