HIV People, Projects and Publications Working on HIV People Kate Grabowski Associate Professor, School of Medicine, Department of Epidemiology Alison Hill Assistant Professor, Department of Biomedical Engineering Amy Wesolowski Assistant Professor, Department of Epidemiology Kyra Grantz PhD Candidate, Department of Epidemiology Anjalika Nande Postdoctoral Fellow, Institute for Computational Medicine Michael Martin Postdoctoral Fellow, Department of Pathology Seungwon Kim Postdoctoral Fellow, School of Medicine Jasmine Wang Mathematical Modeling Researcher, Department of Epidemiology Projects HCV/HIV Modeling in People Who Inject Drugs (PWID) Through this project, we aim to characterize PWID networks in the Baltimore Metropolitan Area to identify risk factors for HIV and HCV transmission in this population and understand how interventions and behavioral changes might impact transmission. HIV and STI Surveillance in Eastern and Southern Africa We work closely with the Rakai Health Sciences Program and other collaborators to study HIV transmission in sub-Saharan Africa. Within-Host HIV Modeling Developing mathematical models of HIV drug action within individual patients to predict the outcomes of novel therapeutics. Publications January 2023 A Moving Target: Impacts of Lowering Viral Load Suppression Cutpoints on Progress Towards HIV Epidemic Control Goals Rosen JG, et al. medRxiv Publication December 2022 The HIV and sexually transmitted infection syndemic following mass scale-up of combination HIV interventions in two communities in southern Uganda: a population-based cross-sectional study Grabowski MK, et al. Lancet Glob Health Publication November 2022 The risk of drug resistance during long-acting antimicrobial therapy Nande A, et al. Proc Biol Sci Publication September 2022 Regression with interval-censored covariates: Application to cross-sectional incidence estimation Morrison D, et al. Biometrics Publication June 2022 High Rates of Pre-exposure Prophylaxis Eligibility and Associated HIV Incidence in a Population With a Generalized HIV Epidemic in Rakai, Uganda Ssempijja V, et al. J Acquir Immune Defic Syndr Publication March 2022 Brief Report: Mobile Phones, Sexual Behaviors, and HIV Incidence in Rakai, Uganda, From 2010 to 2018 Kreniske P, et al. J Acquir Immune Defic Syndr Publication February 2022 A highly virulent variant of HIV-1 circulating in the Netherlands Wymant C, et al. Science Publication January 2022 Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load Zhao L, et al. Virus Evol Publication November 2021 Alcohol use and alcohol-related consequences are associated with not being virally suppressed among persons living with HIV in the Rakai region of Uganda Miller AP, et al. Drug Alcohol Depend Publication September 2021 Declining HIV incidence in sub-Saharan Africa: a systematic review and meta-analysis of empiric data Joshi K, et al. J Int AIDS Soc Publication May 2021 The HIV Screening Cascade: Current Emergency Department-Based Screening Strategies Leave Many Patients With HIV Undiagnosed Mohareb AM, et al. J Acquir Immune Defic Syndr Publication April 2021 Prevalence and Predictors of Persistent Human Immunodeficiency Virus Viremia and Viral Rebound After Universal Test and Treat: A Population-Based Study Grabowski MK, et al. J Infect Dis Publication March 2021 A high prevalence of potential HIV elite controllers identified over 30 years in Democratic Republic of Congo Berg MG, et al. EBioMedicine Publication February 2021 Antigen-driven clonal selection shapes the persistence of HIV-1-infected CD4+ T cells in vivo Simonetti FR, et al. Publication May 2020 Impact of male circumcision on risk of HIV infection in men in a changing epidemic context - systematic review and meta-analysis Farley TM, et al. J Int AIDS Soc Publication May 2020 HIV-1 Subtype Distribution and Diversity Over 18 Years in Rakai, Uganda Lamers SL, et al. AIDS Res Hum Retroviruses Publication March 2020 Quantifying HIV transmission flow between high-prevalence hotspots and surrounding communities: a population-based study in Rakai, Uganda Ratmann O, et al. Lancet HIV Publication February 2020 Migration, hotspots, and dispersal of HIV infection in Rakai, Uganda Kate Grabowski M, et al. Nat Commun Publication September 2019 Impact of combination HIV interventions on HIV incidence in hyperendemic fishing communities in Uganda: a prospective cohort study Kagaayi J, et al. Lancet HIV Publication May 2019 Effect of HIV Subtype and Antiretroviral Therapy on HIV-Associated Neurocognitive Disorder Stage in Rakai, Uganda Sacktor N, et al. J Acquir Immune Defic Syndr Publication April 2019 Characteristics Associated With Human Immunodeficiency Virus Transmission Networks Involving Adolescent Girls and Young Women in Human Immunodeficiency Virus Prevention Trials Network 068 Study Stoner MCD, et al. Sex Transm Dis Publication April 2019 PANGEA-HIV 2: Phylogenetics And Networks for Generalised Epidemics in Africa Curr Opin HIV AIDS Publication March 2019 Validation of the Limiting Antigen Avidity Assay to Estimate Level and Trends in HIV Incidence in an A/D Epidemic in Rakai, Uganda Laeyendecker O, et al. AIDS Res Hum Retroviruses Publication March 2019 Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis Ratmann O, et al. Nat Commun Publication View all diseases
HCV/HIV Modeling in People Who Inject Drugs (PWID) Through this project, we aim to characterize PWID networks in the Baltimore Metropolitan Area to identify risk factors for HIV and HCV transmission in this population and understand how interventions and behavioral changes might impact transmission.
HIV and STI Surveillance in Eastern and Southern Africa We work closely with the Rakai Health Sciences Program and other collaborators to study HIV transmission in sub-Saharan Africa.
Within-Host HIV Modeling Developing mathematical models of HIV drug action within individual patients to predict the outcomes of novel therapeutics.
January 2023 A Moving Target: Impacts of Lowering Viral Load Suppression Cutpoints on Progress Towards HIV Epidemic Control Goals Rosen JG, et al. medRxiv Publication
December 2022 The HIV and sexually transmitted infection syndemic following mass scale-up of combination HIV interventions in two communities in southern Uganda: a population-based cross-sectional study Grabowski MK, et al. Lancet Glob Health Publication
November 2022 The risk of drug resistance during long-acting antimicrobial therapy Nande A, et al. Proc Biol Sci Publication
September 2022 Regression with interval-censored covariates: Application to cross-sectional incidence estimation Morrison D, et al. Biometrics Publication
June 2022 High Rates of Pre-exposure Prophylaxis Eligibility and Associated HIV Incidence in a Population With a Generalized HIV Epidemic in Rakai, Uganda Ssempijja V, et al. J Acquir Immune Defic Syndr Publication
March 2022 Brief Report: Mobile Phones, Sexual Behaviors, and HIV Incidence in Rakai, Uganda, From 2010 to 2018 Kreniske P, et al. J Acquir Immune Defic Syndr Publication
February 2022 A highly virulent variant of HIV-1 circulating in the Netherlands Wymant C, et al. Science Publication
January 2022 Phylogenetic estimation of the viral fitness landscape of HIV-1 set-point viral load Zhao L, et al. Virus Evol Publication
November 2021 Alcohol use and alcohol-related consequences are associated with not being virally suppressed among persons living with HIV in the Rakai region of Uganda Miller AP, et al. Drug Alcohol Depend Publication
September 2021 Declining HIV incidence in sub-Saharan Africa: a systematic review and meta-analysis of empiric data Joshi K, et al. J Int AIDS Soc Publication
May 2021 The HIV Screening Cascade: Current Emergency Department-Based Screening Strategies Leave Many Patients With HIV Undiagnosed Mohareb AM, et al. J Acquir Immune Defic Syndr Publication
April 2021 Prevalence and Predictors of Persistent Human Immunodeficiency Virus Viremia and Viral Rebound After Universal Test and Treat: A Population-Based Study Grabowski MK, et al. J Infect Dis Publication
March 2021 A high prevalence of potential HIV elite controllers identified over 30 years in Democratic Republic of Congo Berg MG, et al. EBioMedicine Publication
February 2021 Antigen-driven clonal selection shapes the persistence of HIV-1-infected CD4+ T cells in vivo Simonetti FR, et al. Publication
May 2020 Impact of male circumcision on risk of HIV infection in men in a changing epidemic context - systematic review and meta-analysis Farley TM, et al. J Int AIDS Soc Publication
May 2020 HIV-1 Subtype Distribution and Diversity Over 18 Years in Rakai, Uganda Lamers SL, et al. AIDS Res Hum Retroviruses Publication
March 2020 Quantifying HIV transmission flow between high-prevalence hotspots and surrounding communities: a population-based study in Rakai, Uganda Ratmann O, et al. Lancet HIV Publication
February 2020 Migration, hotspots, and dispersal of HIV infection in Rakai, Uganda Kate Grabowski M, et al. Nat Commun Publication
September 2019 Impact of combination HIV interventions on HIV incidence in hyperendemic fishing communities in Uganda: a prospective cohort study Kagaayi J, et al. Lancet HIV Publication
May 2019 Effect of HIV Subtype and Antiretroviral Therapy on HIV-Associated Neurocognitive Disorder Stage in Rakai, Uganda Sacktor N, et al. J Acquir Immune Defic Syndr Publication
April 2019 Characteristics Associated With Human Immunodeficiency Virus Transmission Networks Involving Adolescent Girls and Young Women in Human Immunodeficiency Virus Prevention Trials Network 068 Study Stoner MCD, et al. Sex Transm Dis Publication
April 2019 PANGEA-HIV 2: Phylogenetics And Networks for Generalised Epidemics in Africa Curr Opin HIV AIDS Publication
March 2019 Validation of the Limiting Antigen Avidity Assay to Estimate Level and Trends in HIV Incidence in an A/D Epidemic in Rakai, Uganda Laeyendecker O, et al. AIDS Res Hum Retroviruses Publication
March 2019 Inferring HIV-1 transmission networks and sources of epidemic spread in Africa with deep-sequence phylogenetic analysis Ratmann O, et al. Nat Commun Publication
