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Phylogenetic Study Design

Phylogenetic Study Design

Developing methods to estimate informative sample sizes for phylogenetic studies.

Study Designs for Phylogenetic Studies

This work aims to develop a new methodology for relating sample size to phylogenetic inference. This will allow researchers to better design studies that maximize their change of success and make it easier for grant reviewers to evaluate the conclusions of phylogenetic analyses, which are increasingly used to answer public health questions during pathogen outbreaks.
 
Specific goals of this project include developing a framework to determine what portion of inferred transmission links from a phylogenetic analysis are correct and extending this framework beyond questions of direct linkage.
 

Principal Investigator

Justin Lessler Associate Professor

Funders

The Bill and Melinda Gates Foundation

Publications

11 Jul 2020
Sample Size Calculation for Phylogenetic Case Linkage
Wohl S, Giles JR, Lessler J
MedRxiv, 2020: 10.1101/2020.07.10.20150920

Contact

Tel: xxx-xxx-xxxx

Email: iddynam [at] jhu.edu

Infectious Disease Dynamics Group
c/o Amy Wesolowski
Johns Hopkins Bloomberg School of Public Health
615 North Wolfe Street, E6516
Baltimore MD 21205

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