Measles & Rubella Dynamics

Working towards control, elimination, and eradication of one the world's most infectious diseases.

The Measles & Rubella Dynamics project is a collection of work focused on improving and achieving measles and rubella control, elimination, and eradication. To achieve this, we are conducting studies and developing methods to better estimate true vaccination coverage and immunity, estimate risk of outbreaks, identify whether vaccination goals are being met, and inform vaccination strategies and policy.

We are engaged with the WHO Measles Special Advisory Group of Experts (SAGE) to define and respond to existing challenges in reaching the goals of the Measles & Rubella Initiative (http://measlesrubellainitiative.org/). Through this collaboration, and in collaboration with our partners at the University of Princeton, Pennsylvannia State University, and The U.S. Centers for Disease Control, we are working to understand and develop tools to combat the challenges to effective immunization and elimination of these diseases.

Principal Investigator

Justin Lessler Associate Professor

William Moss

Updates #measles

10 months 1 week ago

Congratulations to @Shaun_Truelove on his excellent dissertation defense. A well deserved new PhD from @JohnsHopkinsEPI. #measles
1 year 1 month ago

RT @NatureComms: The geography of #measles vaccination in the African Great Lakes region https://t.co/1eFmeUmkY4 by @JustinLessler… https://t.co/zZlzr6mlSY
1 year 11 months ago

Years in the making, @JustinLessler and @CJEMetcalf's work on triggered vax campaigns out in @PLOSMedicine https://t.co/RRdIaggMci #measles

Funders

The Bill and Melinda Gates Foundation

Collaborators

World Health Organization

US Centers for Disease Control and Prevention

Princeton University

The Pennsylvania State University

Publications

Revealing Measles Outbreak Risk With a Nested IgG Serosurvey in Madagascar .

Winter AK, Wesolowski AP, Mensah KJ, Ramamonjiharisoa MB, Randriamanantena AH, Razafindratsimandresy R, Cauchemez S, Lessler J, Ferrari MJ, Metcalf CJE, Héraud JM.

Am J Epidemiol, 2018: 10.1093/aje/kwy114

Benefits and Challenges in Using Seroprevalence Data to Inform Models for Measles and Rubella Elimination.

Winter AK, Martinez ME, Cutts FT, Moss WJ, Ferrari MJ, McKee A, Lessler J, Hayford K, Wallinga J, Metcalf CJE.

J Infect Dis, 2018: 218(3): 355-364, 10.1093/infdis/jiy137

Challenges and opportunities in disease forecasting in outbreak settings: a case study of measles in Lola Prefecture, Guinea.

Graham M, Suk JE, Takahashi S, Metcalf CJE, Jimenez AP, Prikazsky V, Ferrari MJ, Lessler J.

Am J Trop Med Hyg, 2018: 98(5): 1489 - 149, 10.4269/ajtmh.17-0218

Rubella vaccination in India: identifying broad consequences of vaccine introduction and key knowledge gaps.

Winter AK, Pramanik S, Lessler J, Ferrari M, Grenfell BT, Metcalf CJE.

Epidemiol Infect, 2018: 126(1): 65-77, 10.1017/S0950268817002527

Demographics, epidemiology and the impact of vaccination campaigns in a measles-free world–Can elimination be maintained?

Prada JM, Metcalf CJE, Takahashi S, Lessler J, Tatem AJ, Ferrari M.